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KMID : 0043320010240040276
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Archives of Pharmacal Research
2001 Volume.24 No. 4 p.276 ~ p.280
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Structure-Activity Relationship Studies of Isoquinolinone Type Anticancer Agent
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Cheon SH
Park JS/Lee JY/Lee YN/Yi H/Chung BH/Choi BG/Cho WJ
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Abstract
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Substituted isoquinolin-1 -ones (1) were synthesized to test their in vitrio anticancer activity. 3-Bipheny-N-methylisoquinolin-1-one (7) showed the most potent anticanc er activity against five different human cancer cell lines.
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